Jan
Markiewski

Research student investigating cancer biology and immunology — currently studying renal cell carcinoma mechanisms at Texas Tech Health Sciences Center.

janmarkiewski@gmail.com +1 (325) 338-7686 Abilene, Texas
Experience
Texas Tech Health Sciences Center Jan 2025 – Present
Research Student
Laboratory of Magdalena M. Karbowniczek, M.D., Ph.D. · Abilene, TX
Mechanisms and Signaling Pathways in Mouse Model of Renal Cell Carcinoma
  • Performed computational analysis of RNA sequencing data in RStudio to identify differential gene expression and enriched signaling pathways related to P53 Codon 72 Polymorphism.
  • Developed scientific figures for publications, graphical abstracts, and grant submissions using Adobe Illustrator.
  • Conducted qRT-PCR assays, Western blot analyses, immunofluorescence staining, and confocal microscopy to assess protein localization and cellular phenotypes.
  • Prepared frozen tissue specimens, cryosections, and immunohistochemistry staining to evaluate protein expression within tissue microenvironments.
  • Contributed to NIH grant proposals by editing scientific text, synthesizing literature, and generating supporting experimental figures.
Beth Israel Deaconess Medical Center June 2024
Research Student
Laboratory of Vassiliki A. Boussiotis, M.D., Ph.D. · Boston, MA
Mechanisms and Signaling Pathways of T-Cell Responses
  • Conducted extensive literature review on tumor-infiltrating macrophages, FLT3/FL signaling, cancer immune defense, and the tumor microenvironment.
  • Completed PCR training and performed gel electrophoresis; assisted with mouse model experiments including tumor measurement and analysis.
  • Learned flow cytometry fundamentals on the Cytoflex platform, including gating, compensation, and data analysis for immunological applications.
Texas Tech Health Sciences Center Mar 2023 – Aug 2023
Research Student
Laboratory of Magdalena M. Karbowniczek, M.D., Ph.D. · Abilene, TX
Digital Pathology and Statistical Data Analysis
Accrued 120+ cumulative hours in digital pathology, Western blotting, and statistical data analysis through digital imaging of animal tissue.
Publications
Kalvala, Anil Kumar et al.
Extracellular vesicles modulate integrin signaling and subcellular energetics to promote pulmonary lymphangioleiomyomatosis metastasis.
Communications Biology, vol. 8, no. 1, article 1623 · November 20, 2025
↗ doi:10.1038/s42003-025-09004-9
Education
Academy for Technology, Engineering, Math, and Science
Aug 2022 – May 2027 Junior · Abilene, Texas
1540SAT
1 / 91Class Rank
104.5GPA
Coursework: Introduction to Engineering Design, Computer Integrated Manufacturing, AP Calculus AB, AP Physics 1, AP English Literature & Composition, AP U.S. History, AP World History: Modern, AP Precalculus.
Walldorf Gymnasium
Aug 2024 – Dec 2024 Exchange Student · Walldorf, Germany
Participated in the Congress-Bundestag Youth Exchange (CBYX), studying abroad at Gymnasium Walldorf as a full-time high school student representing the United States.